5-HTP 100mg + B6 — Mood & Sleep Support
5-HTP (Griffonia seed extract) with vitamin B6 — serotonin precursor for mood, sleep, and appetite balance.
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Order dispatched, tracking info sent. Most customers take their first dose the day it arrives.
Research shows it takes ~14 days to anchor a new habit. By now, most customers have found their ideal time of day.
At 8 weeks, customers report the strongest improvements. Consistency is everything with nutritional supplements.
Over 90% of Medibro subscribers are still on the same product at 3 months — the clearest signal a supplement is working.
5-HTP crosses the blood-brain barrier and converts directly to serotonin, the neurotransmitter governing mood, sleep onset, and appetite regulation. We pair it with vitamin B6 (the cofactor for this conversion) at a meaningful dose of 10mg.
Each capsule provides 100mg 5-HTP from Griffonia simplicifolia seed extract — standardised to 98% purity.
Benefits
- ✓Mood support
- ✓Sleep onset
- ✓Appetite regulation
- ✓Serotonin production
- ✓Carbohydrate cravings
Complete your stack
✨What customers say
From 20 reviews★ 4.5Customers appreciate the noticeable improvement in mood and sleep quality, particularly during winter months, with many highlighting the effectiveness of the B6 combination for serotonin synthesis.
Some users mention the need for patience, as it can take up to three weeks to see results, and there are strong warnings against combining it with SSRIs.
This product is best for individuals seeking natural support for mood enhancement and sleep improvement, particularly those experiencing seasonal mood dips or low-grade anxiety.
Customer reviews
- ★★★★☆Noah H.17/05/2026Important: do not combine with SSRIs
Cannot stress enough that 5-HTP should not be taken with antidepressants. For those without medication, it is a useful tool.
- ★★★★★Henry I.16/05/2026Good for seasonal mood
Winter mood is always my weak point. 5-HTP has taken the edge off and improved my sleep quality simultaneously.
- ★★★★☆Hannah O.16/05/2026Important: do not combine with SSRIs
Cannot stress enough that 5-HTP should not be taken with antidepressants. For those without medication, it is a useful tool.
- ★★★★☆Hannah O.30/04/2026Works differently to antidepressants
Do not expect immediate results. After 3 weeks my mood baseline is notably higher and I fall asleep more easily.
- ★★★★★Hannah C.Verified buyer30/04/2026Mood genuinely lifted
Been taking this for 6 weeks alongside a good sleep routine. The combination of 5-HTP and B6 is well-established — B6 is the cofactor for serotonin synthesis. I sleep better and feel more positive in the mornings. Not a miracle but a real, noticeable shift.
- ★★★★★Sarah M.26/04/2026Mood lifted within two weeks
I take this in the evening and my mood and sleep have both improved. The B6 combination helps with serotonin synthesis.
- ★★★★★Sophie R.21/04/2026Good for seasonal mood
Winter mood is always my weak point. 5-HTP has taken the edge off and improved my sleep quality simultaneously.
- ★★★★☆Jack N.18/04/2026Important: do not combine with SSRIs
Cannot stress enough that 5-HTP should not be taken with antidepressants. For those without medication, it is a useful tool.
- ★★★★★William L.07/04/2026Mood lifted within two weeks
I take this in the evening and my mood and sleep have both improved. The B6 combination helps with serotonin synthesis.
- ★★★★★Finley X.04/04/2026Mood lifted within two weeks
I take this in the evening and my mood and sleep have both improved. The B6 combination helps with serotonin synthesis.
- ★★★★☆Hannah O.04/04/2026Works differently to antidepressants
Do not expect immediate results. After 3 weeks my mood baseline is notably higher and I fall asleep more easily.
- ★★★★☆Freya Z.01/04/2026Works differently to antidepressants
Do not expect immediate results. After 3 weeks my mood baseline is notably higher and I fall asleep more easily.
- ★★★★☆Chloe V.30/03/2026Works differently to antidepressants
Do not expect immediate results. After 3 weeks my mood baseline is notably higher and I fall asleep more easily.
- ★★★★★Ella U.27/03/2026Good for seasonal mood
Winter mood is always my weak point. 5-HTP has taken the edge off and improved my sleep quality simultaneously.
- ★★★★★Sophie R.24/03/2026Mood lifted within two weeks
I take this in the evening and my mood and sleep have both improved. The B6 combination helps with serotonin synthesis.
- ★★★★★Jack N.05/03/2026Good for seasonal mood
Winter mood is always my weak point. 5-HTP has taken the edge off and improved my sleep quality simultaneously.
- ★★★★★Thomas R.Verified buyer05/03/2026Works well for serotonin support
Functional medicine practitioner friend recommended 5-HTP for seasonal mood dips. The B6 addition is key — it converts 5-HTP to serotonin. Noticeably calmer, better sleep, more even mood.
- ★★★★☆Laura S.Verified buyer22/02/2026Good quality, takes 3 weeks
Patience required — took 3 weeks to notice anything. Now sleep is consistently better and mood is more stable through the day. Good quality capsules, no stomach issues.
- ★★★★★Jordan M.Verified buyer23/11/2025Finally something that helps my mood
I was reluctant to try supplements for mood but my nutritionist suggested 5-HTP as a first step. After 4 weeks the low-grade anxiety is quieter and I sleep more soundly. Proper dose, proper form.
- ★★★★☆Alicia B.07/10/2025Good sleep supplement
Taking this 45 minutes before bed as recommended. Falls asleep faster and the 3am wake-ups are much less frequent. The B6 addition makes sense — absorption is better. Would recommend.
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