5-HTP 100mg + B6 — Mood & Sleep Support
5-HTP (Griffonia seed extract) with vitamin B6 — serotonin precursor for mood, sleep, and appetite balance.
What does optimal health cost per day?
Less than a coffee top-up. Optimal nutrition for 28p/day — the most cost-effective investment in your health.
Free Vitamin C 1000mg with orders over £40
While stocks last · auto-added at checkout
Supply size
Most customers reorder this monthly. Each pack lasts ~30 days.
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Your daily health investment
£0.47
per day
£3.29
per week
£13.99
per month
Less than a daily coffee — for daily nutritional support from 5-HTP 100mg.
Auto-delivered. No minimum term. Cancel any time.
Price locked forever — we never raise your subscription price. Cancel any time, no fees.
Bundle and save up to 20%
Add 2+ products to your stack — discount applied automatically at checkout.
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Only £2.99 — credited toward your first full order
Group buy — save up to 30%
Limited spotsPool orders with other 5-HTP buyers. The more people join, the more everyone saves. Next group buy runs when we hit 50 registrations.
📦 What to expect when it arrives
Premium box
Double-sealed. No cheap poly bags — every Medibro order ships in a quality box.
Amber glass
UV-protective amber glass preserves potency. Satisfying click-lid seal.
Little extras
Every first order includes a usage guide and a surprise freebie — see what you get.
Start today
Take your first dose the day it arrives — don't wait for a 'perfect moment'.
Your 30-day journey starts today
Future you will look back on this moment.
Based on typical customer reports. Individual results vary. Backed by our 30-day guarantee.
Premium packaging, inside and out
Amber glass jar
Blocks UV degradation, no plastic leaching
100% recyclable
Jar, cap, and box are fully kerbside recyclable
No artificial fillers
No magnesium stearate, silicon dioxide, or titanium dioxide
- Free UK delivery over £35
- 14-day hassle-free returns
- Secure checkout, audit-logged
- Manually compliance-reviewed
Order dispatched, tracking info sent. Most customers take their first dose the day it arrives.
Research shows it takes ~14 days to anchor a new habit. By now, most customers have found their ideal time of day.
At 8 weeks, customers report the strongest improvements. Consistency is everything with nutritional supplements.
Over 90% of Medibro subscribers are still on the same product at 3 months — the clearest signal a supplement is working.
5-HTP crosses the blood-brain barrier and converts directly to serotonin, the neurotransmitter governing mood, sleep onset, and appetite regulation. We pair it with vitamin B6 (the cofactor for this conversion) at a meaningful dose of 10mg.
Each capsule provides 100mg 5-HTP from Griffonia simplicifolia seed extract — standardised to 98% purity.
Benefits
- ✓Mood support
- ✓Sleep onset
- ✓Appetite regulation
- ✓Serotonin production
- ✓Carbohydrate cravings
Dosing Guide
How to take 5-HTP 100mg + B6 — Mood & Sleep Support
Take 1 capsule 30–60 minutes before bed. Do not exceed 2 capsules per day.
Always read the label. Consult a healthcare professional if you have any medical conditions or take prescription medication.
Quality & transparency
How we compare
Medibro vs. typical high-street / marketplace alternatives
| Feature | Medibro | Others |
|---|---|---|
| Ingredient quality | Premium grade | Generic grade |
| Third-party tested | ||
| No unnecessary fillers | ||
| UK manufactured | ||
| 30-day guarantee | ||
| Free UK shipping from £35 |
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⏰ How to take for best results
Best time
With food, once daily
Take with
Water or a meal
Avoid with
No specific interactions — check with your GP if on medication
Consistency is key. Take at the same time each day to build habit and maximise benefit.
Frequently asked questions
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Answer 4 quick questions and get a personalised stack built around your goals, health history, and lifestyle.
Medibro Quality Score™
Independent assessmentPurity
92
Overall
out of 100
Potency
Value
How we compare
Medibro | Budget | Pharmacy | |
|---|---|---|---|
3rd-party COA testing | |||
Premium forms (glycinate, KSM-66, TG omega) | |||
Full ingredient transparency | |||
UK pharmacist reviewed | |||
No proprietary blends | |||
30-day money-back guarantee | |||
Eco-friendly packaging |
Comparison reflects general market observations. Specific brands may vary.
What outcomes matter most to you?
Founded by a UK pharmacist
“After 12 years dispensing prescriptions, I was frustrated by the gap between expensive supplements and what the evidence actually supports. Medibro was built to source properly — clinical doses, verified purity, fair prices.”
— MPharm, GPhC registered · Medibro founder
Every formula is reviewed by our in-house pharmacy team before launch.
Complete your stack
✨What customers say
From 20 reviews★ 4.5Customers appreciate the noticeable improvement in mood and sleep quality, especially during seasonal changes, with many highlighting the effectiveness of the B6 combination for serotonin synthesis.
Some users mention the need for patience, as it can take up to three weeks to see significant results, and there are strong warnings against combining it with SSRIs.
This product is ideal for individuals seeking natural support for mood enhancement and sleep improvement, particularly those experiencing seasonal mood dips or low-grade anxiety.
Customer reviews
- ★★★★☆Noah H.03/05/2026Important: do not combine with SSRIs
Cannot stress enough that 5-HTP should not be taken with antidepressants. For those without medication, it is a useful tool.
- ★★★★★Henry I.03/05/2026Good for seasonal mood
Winter mood is always my weak point. 5-HTP has taken the edge off and improved my sleep quality simultaneously.
- ★★★★☆Hannah O.02/05/2026Important: do not combine with SSRIs
Cannot stress enough that 5-HTP should not be taken with antidepressants. For those without medication, it is a useful tool.
- ★★★★☆Hannah O.16/04/2026Works differently to antidepressants
Do not expect immediate results. After 3 weeks my mood baseline is notably higher and I fall asleep more easily.
- ★★★★★Hannah C.Verified buyer16/04/2026Mood genuinely lifted
Been taking this for 6 weeks alongside a good sleep routine. The combination of 5-HTP and B6 is well-established — B6 is the cofactor for serotonin synthesis. I sleep better and feel more positive in the mornings. Not a miracle but a real, noticeable shift.
- ★★★★★Sarah M.12/04/2026Mood lifted within two weeks
I take this in the evening and my mood and sleep have both improved. The B6 combination helps with serotonin synthesis.
- ★★★★★Sophie R.07/04/2026Good for seasonal mood
Winter mood is always my weak point. 5-HTP has taken the edge off and improved my sleep quality simultaneously.
- ★★★★☆Jack N.04/04/2026Important: do not combine with SSRIs
Cannot stress enough that 5-HTP should not be taken with antidepressants. For those without medication, it is a useful tool.
- ★★★★★William L.24/03/2026Mood lifted within two weeks
I take this in the evening and my mood and sleep have both improved. The B6 combination helps with serotonin synthesis.
- ★★★★★Finley X.21/03/2026Mood lifted within two weeks
I take this in the evening and my mood and sleep have both improved. The B6 combination helps with serotonin synthesis.
- ★★★★☆Hannah O.21/03/2026Works differently to antidepressants
Do not expect immediate results. After 3 weeks my mood baseline is notably higher and I fall asleep more easily.
- ★★★★☆Freya Z.19/03/2026Works differently to antidepressants
Do not expect immediate results. After 3 weeks my mood baseline is notably higher and I fall asleep more easily.
- ★★★★☆Chloe V.17/03/2026Works differently to antidepressants
Do not expect immediate results. After 3 weeks my mood baseline is notably higher and I fall asleep more easily.
- ★★★★★Ella U.13/03/2026Good for seasonal mood
Winter mood is always my weak point. 5-HTP has taken the edge off and improved my sleep quality simultaneously.
- ★★★★★Sophie R.10/03/2026Mood lifted within two weeks
I take this in the evening and my mood and sleep have both improved. The B6 combination helps with serotonin synthesis.
- ★★★★★Jack N.20/02/2026Good for seasonal mood
Winter mood is always my weak point. 5-HTP has taken the edge off and improved my sleep quality simultaneously.
- ★★★★★Thomas R.Verified buyer19/02/2026Works well for serotonin support
Functional medicine practitioner friend recommended 5-HTP for seasonal mood dips. The B6 addition is key — it converts 5-HTP to serotonin. Noticeably calmer, better sleep, more even mood.
- ★★★★☆Laura S.Verified buyer08/02/2026Good quality, takes 3 weeks
Patience required — took 3 weeks to notice anything. Now sleep is consistently better and mood is more stable through the day. Good quality capsules, no stomach issues.
- ★★★★★Jordan M.Verified buyer09/11/2025Finally something that helps my mood
I was reluctant to try supplements for mood but my nutritionist suggested 5-HTP as a first step. After 4 weeks the low-grade anxiety is quieter and I sleep more soundly. Proper dose, proper form.
- ★★★★☆Alicia B.23/09/2025Good sleep supplement
Taking this 45 minutes before bed as recommended. Falls asleep faster and the 3am wake-ups are much less frequent. The B6 addition makes sense — absorption is better. Would recommend.
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