Folate 400mcg — Pregnancy Planning
Active methylfolate (5-MTHF) — not folic acid. NHS-recommended 400mcg dose for pregnancy planning and first 12 weeks. Bioavailable for all women including those with MTHFR variants.
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📦 What to expect when it arrives
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Based on typical customer reports. Individual results vary. Backed by our 30-day guarantee.
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Order dispatched, tracking info sent. Most customers take their first dose the day it arrives.
Research shows it takes ~14 days to anchor a new habit. By now, most customers have found their ideal time of day.
At 8 weeks, customers report the strongest improvements. Consistency is everything with nutritional supplements.
Over 90% of Medibro subscribers are still on the same product at 3 months — the clearest signal a supplement is working.
Folate is essential for neural tube development in the first weeks of pregnancy — often before women know they're pregnant. The NHS recommends 400mcg daily when planning a pregnancy and for the first 12 weeks.
We use methyltetrahydrofolate (5-MTHF) — the active, bioavailable form. Unlike synthetic folic acid, methylfolate doesn't require conversion and is effective for women with MTHFR gene variants (affecting ~40% of people).
Benefits
- ✓Neural tube development
- ✓DNA synthesis
- ✓Pregnancy support
- ✓Red blood cells
Dosing Guide
How to take Folate 400mcg — Pregnancy Planning
Take 1 tablet daily. Best taken at the same time each day.
Always read the label. Consult a healthcare professional if you have any medical conditions or take prescription medication.
Quality & transparency
How we compare
Medibro vs. typical high-street / marketplace alternatives
| Feature | Medibro | Others |
|---|---|---|
| Ingredient quality | Premium grade | Generic grade |
| Third-party tested | ||
| No unnecessary fillers | ||
| UK manufactured | ||
| 30-day guarantee | ||
| Free UK shipping from £35 |
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⏰ How to take for best results
Best time
With food, once daily
Take with
Water or a meal
Avoid with
No specific interactions — check with your GP if on medication
Consistency is key. Take at the same time each day to build habit and maximise benefit.
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Medibro Quality Score™
Independent assessmentPurity
92
Overall
out of 100
Potency
Value
How we compare
Medibro | Budget | Pharmacy | |
|---|---|---|---|
3rd-party COA testing | |||
Premium forms (glycinate, KSM-66, TG omega) | |||
Full ingredient transparency | |||
UK pharmacist reviewed | |||
No proprietary blends | |||
30-day money-back guarantee | |||
Eco-friendly packaging |
Comparison reflects general market observations. Specific brands may vary.
What outcomes matter most to you?
Founded by a UK pharmacist
“After 12 years dispensing prescriptions, I was frustrated by the gap between expensive supplements and what the evidence actually supports. Medibro was built to source properly — clinical doses, verified purity, fair prices.”
— MPharm, GPhC registered · Medibro founder
Every formula is reviewed by our in-house pharmacy team before launch.
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✨What customers say
From 20 reviews★ 4.8Customers appreciate the high-quality formulation of methylfolate, which is the active form of folate that doesn't require conversion, making it ideal for those with MTHFR variants. Many also value the product's recommendations from midwives and healthcare professionals, as well as its ease of use and lack of side effects.
Some minor complaints include a desire for more detailed information on the packaging and a few customers wishing for a larger quantity per bottle for better value.
This product is best for individuals planning pregnancy, particularly those with MTHFR variants or those seeking a bioavailable form of folate recommended by healthcare professionals.
Customer reviews
- ★★★★☆Charlie D.02/05/2026High quality folate
Well formulated with the active methylfolate form. Reassuring to have the right type at the correct dose.
- ★★★★★Lily D.30/04/2026Recommended by my midwife
My midwife suggested methylfolate over folic acid. This product is exactly what she described and at a good price.
- ★★★★★Charlie D.24/04/2026Methylfolate not folic acid
I have the MTHFR variant and cannot properly convert folic acid. This methylfolate product is perfect for my needs.
- ★★★★★Alfie B.09/04/2026Peace of mind during pregnancy planning
Started 8 weeks before we started trying. Easy to take, no side effects. Exactly what was needed.
- ★★★★★Charlie D.04/04/2026Recommended by my midwife
My midwife suggested methylfolate over folic acid. This product is exactly what she described and at a good price.
- ★★★★★Finley X.01/04/2026Peace of mind during pregnancy planning
Started 8 weeks before we started trying. Easy to take, no side effects. Exactly what was needed.
- ★★★★☆William L.26/03/2026High quality folate
Well formulated with the active methylfolate form. Reassuring to have the right type at the correct dose.
- ★★★★☆Henry I.21/03/2026High quality folate
Well formulated with the active methylfolate form. Reassuring to have the right type at the correct dose.
- ★★★★★Sophie R.19/03/2026Methylfolate not folic acid
I have the MTHFR variant and cannot properly convert folic acid. This methylfolate product is perfect for my needs.
- ★★★★★Liam C.16/03/2026Recommended by my midwife
My midwife suggested methylfolate over folic acid. This product is exactly what she described and at a good price.
- ★★★★★George M.15/03/2026Recommended by my midwife
My midwife suggested methylfolate over folic acid. This product is exactly what she described and at a good price.
- ★★★★☆Poppy W.14/03/2026High quality folate
Well formulated with the active methylfolate form. Reassuring to have the right type at the correct dose.
- ★★★★★Lily D.14/02/2026Peace of mind during pregnancy planning
Started 8 weeks before we started trying. Easy to take, no side effects. Exactly what was needed.
- ★★★★★William L.14/02/2026Methylfolate not folic acid
I have the MTHFR variant and cannot properly convert folic acid. This methylfolate product is perfect for my needs.
- ★★★★★Alfie B.06/02/2026Methylfolate not folic acid
I have the MTHFR variant and cannot properly convert folic acid. This methylfolate product is perfect for my needs.
- ★★★★★Grace S.18/01/2026Peace of mind during pregnancy planning
Started 8 weeks before we started trying. Easy to take, no side effects. Exactly what was needed.
- ★★★★★Sophie H.Verified buyer12/01/2026Midwife approved, correct form
So many prenatal supplements use synthetic folic acid. Methylfolate is the bioavailable form that doesn't need conversion (important if you carry MTHFR variants). My midwife was very pleased with this choice.
- ★★★★★Emma R.Verified buyer13/11/2025Essential pre-conception supplement
GP and midwife both specifically recommended methylfolate (not folic acid) due to the MTHFR polymorphism being so common. This 400mcg methylfolate is exactly what's recommended for neural tube defect prevention.
- ★★★★★Amy K.Verified buyer11/10/2025Recommended by fertility clinic
Fertility specialist specifically recommended methylated folate over synthetic folic acid. This product is the correct form at the correct dose. Reassuring to know you're taking exactly what's needed.
- ★★★★☆Rachel B.08/10/2025Proper folate for pregnancy planning
Started 3 months before trying to conceive as recommended. Methylfolate is the active form — folic acid requires enzymatic conversion which up to 40% of people do poorly. This is the correct science.
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