Vitamin B12 Methylcobalamin 1000mcg
Methylcobalamin — the active, neurologically-superior form of B12. Essential for vegans, vegetarians, and anyone on metformin or PPIs.
What does optimal health cost per day?
Less than a coffee top-up. Optimal nutrition for 21p/day — the most cost-effective investment in your health.
Free Vitamin C 1000mg with orders over £40
While stocks last · auto-added at checkout
Supply size
Most customers reorder this monthly. Each pack lasts ~30 days.
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Your daily health investment
£0.28
per day
£1.96
per week
£8.49
per month
Less than a daily coffee — for daily nutritional support from Vitamin B12.
Auto-delivered. No minimum term. Cancel any time.
Price locked forever — we never raise your subscription price. Cancel any time, no fees.
Bundle and save up to 20%
Add 2+ products to your stack — discount applied automatically at checkout.
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Only £2.99 — credited toward your first full order
Group buy — save up to 30%
Limited spotsPool orders with other Vitamin buyers. The more people join, the more everyone saves. Next group buy runs when we hit 50 registrations.
📦 What to expect when it arrives
Premium box
Double-sealed. No cheap poly bags — every Medibro order ships in a quality box.
Amber glass
UV-protective amber glass preserves potency. Satisfying click-lid seal.
Little extras
Every first order includes a usage guide and a surprise freebie — see what you get.
Start today
Take your first dose the day it arrives — don't wait for a 'perfect moment'.
Your 30-day journey starts today
Future you will look back on this moment.
Based on typical customer reports. Individual results vary. Backed by our 30-day guarantee.
Premium packaging, inside and out
Amber glass jar
Blocks UV degradation, no plastic leaching
100% recyclable
Jar, cap, and box are fully kerbside recyclable
No artificial fillers
No magnesium stearate, silicon dioxide, or titanium dioxide
- Free UK delivery over £35
- 14-day hassle-free returns
- Secure checkout, audit-logged
- Manually compliance-reviewed
Order dispatched, tracking info sent. Most customers take their first dose the day it arrives.
Research shows it takes ~14 days to anchor a new habit. By now, most customers have found their ideal time of day.
At 8 weeks, customers report the strongest improvements. Consistency is everything with nutritional supplements.
Over 90% of Medibro subscribers are still on the same product at 3 months — the clearest signal a supplement is working.
Vitamin B12 deficiency is the most common nutritional deficiency in vegans and vegetarians, and is increasingly common in older adults and people on metformin or acid-suppressing medication.
Our sublingual (dissolve-under-tongue) tablets bypass the stomach's absorption pathway — bypassing the need for intrinsic factor. This makes them effective even in people with absorption problems.
Benefits
- ✓Energy
- ✓Mood
- ✓Nerve health
- ✓Brain function
- ✓Red blood cells
Dosing Guide
How to take Vitamin B12 Methylcobalamin 1000mcg
Dissolve 1 tablet under the tongue daily, or as directed by your healthcare professional.
Always read the label. Consult a healthcare professional if you have any medical conditions or take prescription medication.
Quality & transparency
Why form matters
Medibro uses
D3 + K2 (MK-7 form)
Long-acting MK-7
Others often use
D3 alone or K2 as MK-4
Lower bioavailability
MK-7 has a 72-hour half-life vs. MK-4's 1-hour — meaning it's active in your system all week.
K2 directs calcium to bones rather than arteries. Without K2, high-dose D3 can lead to soft-tissue calcium deposits. MK-7 is the clinically preferred form.
How we compare
Medibro vs. typical high-street / marketplace alternatives
| Feature | Medibro | Others |
|---|---|---|
| Ingredient quality | Premium grade | Generic grade |
| Third-party tested | ||
| No unnecessary fillers | ||
| UK manufactured | ||
| 30-day guarantee | ||
| Free UK shipping from £35 |
NHS recommends vitamin D supplementation
The NHS advises everyone in the UK to consider taking 10mcg vitamin D daily, especially from October to March when sunlight is insufficient.
Source: NHS.uk — Vitamin D
Vitamin D3 is more effective with:
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Your personalised stack
Recommended to pair with Vitamin B12
What to expect over time
Blood serum vitamin D starts climbing. Most people don't notice changes yet — this is normal.
Serotonin synthesis improves with adequate D3. Many users notice improved mood and reduced fatigue.
T-cell activation is D3-dependent. Cold and flu resilience measurably improves.
Bone density, cardiovascular and cognitive benefits accumulate. Annual blood test should show 75–200 nmol/L.
⏰ How to take for best results
Best time
With food, once daily
Take with
Water or a meal
Avoid with
No specific interactions — check with your GP if on medication
Consistency is key. Take at the same time each day to build habit and maximise benefit.
Frequently asked questions
Find your perfect supplement stack
Answer 4 quick questions and get a personalised stack built around your goals, health history, and lifestyle.
Medibro Quality Score™
Independent assessmentPurity
92
Overall
out of 100
Potency
Value
How we compare
Medibro | Budget | Pharmacy | |
|---|---|---|---|
3rd-party COA testing | |||
Premium forms (glycinate, KSM-66, TG omega) | |||
Full ingredient transparency | |||
UK pharmacist reviewed | |||
No proprietary blends | |||
30-day money-back guarantee | |||
Eco-friendly packaging |
Comparison reflects general market observations. Specific brands may vary.
What outcomes matter most to you?
Founded by a UK pharmacist
“After 12 years dispensing prescriptions, I was frustrated by the gap between expensive supplements and what the evidence actually supports. Medibro was built to source properly — clinical doses, verified purity, fair prices.”
— MPharm, GPhC registered · Medibro founder
Every formula is reviewed by our in-house pharmacy team before launch.
Stack Synergies
Science-backed pairings for better results
Classic immune duo — Vitamin C and zinc attack pathogens through completely different pathways
Vitamin C is the essential co-factor for collagen synthesis — non-negotiable pairing for skin and joints
Take together to dramatically enhance non-haem iron absorption from food and supplements
Synergies based on published nutritional science. Individual results may vary. Always consult a healthcare professional before combining supplements.
Complete your stack
✨What customers say
From 20 reviews★ 4.5Customers appreciate the high dose of 1,000mcg of methylcobalamin, which is effective for energy levels and nerve health, especially when taken sublingually for optimal absorption.
Some users mentioned that the taste of the sublingual tablets could be improved, and a few found the dosage too high for their needs.
This product is ideal for vegans and vegetarians, individuals with pernicious anaemia, and anyone seeking to improve their energy levels and nerve health.
Customer reviews
- ★★★★☆Henry I.18/04/2026Good dose and form
1,000mcg of methylcobalamin daily covers any deficiency and then some. Well above the RNI to account for absorption losses.
- ★★★★☆Freya Z.08/04/2026Good dose and form
1,000mcg of methylcobalamin daily covers any deficiency and then some. Well above the RNI to account for absorption losses.
- ★★★★★Charlie D.21/03/2026The methylated form makes a difference
Switched from cyanocobalamin to methylcobalamin and the difference in energy levels was noticeable within 2 weeks.
- ★★★★★George H.Verified buyer20/03/2026Vegan — this is essential
Plant-based diet requires B12 supplementation without exception. Methylcobalamin is the active form that doesn't require liver conversion. Nerve function, energy, and cognitive clarity all excellent after 18 months on this.
- ★★★★★Emma W.08/03/2026The methylated form makes a difference
Switched from cyanocobalamin to methylcobalamin and the difference in energy levels was noticeable within 2 weeks.
- ★★★★☆Joshua E.02/03/2026Good dose and form
1,000mcg of methylcobalamin daily covers any deficiency and then some. Well above the RNI to account for absorption losses.
- ★★★★☆Sarah M.28/02/2026Works under the tongue
Sublingual absorption is excellent. Let it dissolve under the tongue rather than swallowing for fastest absorption.
- ★★★★☆William L.26/02/2026Works under the tongue
Sublingual absorption is excellent. Let it dissolve under the tongue rather than swallowing for fastest absorption.
- ★★★★★Amelia K.20/02/2026Essential for vegans
Plant foods contain no B12. This methylcobalamin supplement is a non-negotiable for anyone eating vegan or vegetarian.
- ★★★★★Ava Q.15/02/2026Essential for vegans
Plant foods contain no B12. This methylcobalamin supplement is a non-negotiable for anyone eating vegan or vegetarian.
- ★★★★★Ava Q.11/02/2026The methylated form makes a difference
Switched from cyanocobalamin to methylcobalamin and the difference in energy levels was noticeable within 2 weeks.
- ★★★★☆Isla P.10/02/2026Works under the tongue
Sublingual absorption is excellent. Let it dissolve under the tongue rather than swallowing for fastest absorption.
- ★★★★★Liam C.07/02/2026Essential for vegans
Plant foods contain no B12. This methylcobalamin supplement is a non-negotiable for anyone eating vegan or vegetarian.
- ★★★★☆Noah H.28/01/2026Works under the tongue
Sublingual absorption is excellent. Let it dissolve under the tongue rather than swallowing for fastest absorption.
- ★★★★★Jack N.26/01/2026Essential for vegans
Plant foods contain no B12. This methylcobalamin supplement is a non-negotiable for anyone eating vegan or vegetarian.
- ★★★★★Thomas A.21/01/2026The methylated form makes a difference
Switched from cyanocobalamin to methylcobalamin and the difference in energy levels was noticeable within 2 weeks.
- ★★★★☆Rachel T.Verified buyer17/10/2025Energy and nerve health
Fatigue and mild neuropathy linked to suboptimal B12. 3 months on methylcobalamin 1000mcg and energy is measurably improved. The methylcobalamin form is directly usable by the nervous system.
- ★★★★★Ellen M.Verified buyer15/10/2025B12 levels finally optimal
Serum B12 was bottom of range for years on cyanocobalamin supplements. Switched to methylcobalamin 1000mcg. Blood test 3 months later: B12 well into optimal range. Fatigue improved, memory sharper, pins and needles in feet gone.
- ★★★★★Ian C.02/09/2025Better than injections for me
Started B12 injections for deficiency but they're inconvenient. Switched to 1000mcg methylcobalamin sublingual with GP approval. Blood tests confirm equivalent absorption. More convenient and effective.
- ★★★★☆Patricia N.Verified buyer05/08/2025Pernicious anaemia management
PA means I can't absorb B12 from food. High-dose sublingual methylcobalamin bypasses intrinsic factor dependence via buccal absorption. GP confirmed this approach is effective. B12 levels now consistently optimal.
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